There's a very strong link between food and mood. I have certainly noticed this in my experience, and studies have been conducted that support this. And it makes sense--if what you eat impacts your physical health, how could it not affect mental health? Your mind is part of your body, afterall! High quality fats, protein, and whole, unrefined carbohydrates literally contain the building blocks for every cell in your body, including the neurons in your brain. Processed and refined foods have been around for a relatively short time evolutionarily speaking, and although our bodies are exquisitely capable of breaking them down and using them to sustain us, the fuel is less than ideal, and in some cases, very damaging. In recent history since these foods have been introduced, obesity, diabetes, cardiovascular diseases, and other noncommunicable diseases have taken over as the leading cause of death worldwide (ref). I'd say that's one experiment that is failing, and it's time to return to the unprocessed foods of our ancestors, including a drastic reduction in refined sugar consumption.
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